Arthritis
Abstract: "There are 2 types of joint problems that can occur in patients with inflammatory bowel disease (IBD): arthritis, which is inflammation, and arthralgia, which is pain without inflammation. Arthralgia is more common among patients with IBD, occurring in 40-50% of patients, which is a rate similar to that of the general population;
arthritis occurs in approximately 15—20% of Crohn's disease (CD) patients and approximately 10% of ulcerative colitis (UC) patients at some stage during their disease course."
1. Orchard TR. Chapter 43, Extraintestinal manifestations; skin, joints and mucotanous manifestations. In: Satsangi J, Sutherland LR, editors. Inflammatory Bowel disease. Philadelphia: Elsevier; 2003. pp. 669–697. [Google Scholar]2. Management of arthritis in patients with inflammatory Bowel disease. Gastroenterol Hepatol. 2012;8:327–329. [Google Scholar]3. Relationship between Ulcerative Colitis and Rheumatoid Arthritis - A Review
Abstract: "Ulcerative colitis (UC) is a colonic disease characterized by chronic inflammation. Rheumatoid arthritis (RA) is a rheumatological chronic inflammatory disease characterized by joint swelling and tenderness. It is also considered an autoimmune disorder. We want to discover if a link exists between UC and RA and if so, how UC affects the progress of arthritis.
All these findings provide sufficient evidence that there is a relation between the two diseases. This study is beneficial as it reviews data collected from the last 50 years from different databases, including all cases that have both diseases. It will help scientists and doctors to understand individual and shared elements of both disorders better."
Attalla M G, Singh S B, Khalid R, et al. (September 18, 2019) Relationship between Ulcerative Colitis and Rheumatoid Arthritis - A Review. Cureus 11(9): e5695. doi:10.7759/cureus.5695 Relationship between ulcerative colitis and rheumatoid arthritis - a review------------------------------------------------------------------------------------------------------------------------------------------
Allergies
4. Abstract: "The co-existence of allergic rhinitis (AR) and obstructive sleep apnea (OSA) is a common phenomenon in clinical practice. AR has long been considered a risk factor for OSA. However, the relationship is not completely clear. Therefore, we conducted a meta-analysis to evaluate the prevalence of AR in sleep-disordered breathing (SDB) /OSA and their relationship.
Conclusion: The prevalence of AR in OSA/SDB is considerably high and children with SDB suffering from a higher incidence of AR ...."
Cao Y, Wu S, Zhang L, Yang Y, Cao S, Li Q. Association of allergic rhinitis with obstructive sleep apnea: A meta-analysis. Medicine (Baltimore). 2018 Dec;97(51):e13783. doi: 10.1097/MD.0000000000013783. PMID: 30572534; PMCID: PMC6319794. Co-existence of allergic rhinitis (AR) and obstructive sleep apnea (OSA)5. Sleep-disordered breathing and allergies: "Sleep-disordered breathing is also more common in patients with allergic diseases. Upper and lower airway resistance can increase the risk for sleep-disordered breathing events. In patients with allergic rhinitis, nasal congestion is a risk factor for apnea and snoring.
In summary, sleep impairment associated with allergic diseases, such as asthma, AR, and AD, can have a significant effect on the patient’s quality of life and functioning in specific areas."
Koinis-Mitchell D, Craig T, Esteban CA, Klein RB. Sleep and allergic disease: a summary of the literature and future directions for research. J Allergy Clin Immunol. 2012 Dec;130(6):1275-81. doi: 10.1016/j.jaci.2012.06.026. Epub 2012 Aug 3. PMID: 22867694; PMCID: PMC3576835.
Sleep-disordered breathing and allergies6. Anxiety and Depression in Asthma: "There is growing awareness of the correlation between psychological factors, the course of asthma, and the outcomes of asthma treatment. However, the implications of this correlation are still poorly understood.........
Even though it is generally accepted that anxiety and depression are more common in asthmatic patients and that there is a close correlation between psychological disorders and asthma outcomes, such as poorer control of asthma symptoms, the implications and practical consequences of this link remain weak"
Di Marco F, Santus P, Centanni S. Anxiety and depression in asthma. Curr Opin Pulm Med. 2011 Jan;17(1):39-44. doi: 10.1097/MCP.0b013e328341005f. PMID: 20975562.
Anxiety and depression in Asthmatics