TMJ 'dysfunction' - Health implications

The Cholesterol heart Disease controversy.

Uffe Ravnskov was a Danish independent researcher and a specialist in internal medicine and clinical chemistry, known for his unconventional beliefs regarding the connection between cholesterol and heart disease. He conducted various studies which challenged the universally accepted idea that high cholesterol levels lead to heart disease.

Ravnskov suggested that high cholesterol is not the actual cause of heart disease and criticized the pharmaceutical companies for advertising and selling anti-cholesterol drugs. According to him, these drugs could cause other diseases and conditions. His claims have generated significant controversy within the scientific and medical community. However, some researchers agreed that there is not enough evidence to suggest a direct link between cholesterol levels and heart disease.

Ravnskov has authored several books, including The Cholesterol Myths and Fat and Cholesterol are Good for You. His research and theories have been both praised and criticized. Despite facing backlash from many medical experts, he has always maintained his stance on the cholesterol-heart disease theory.

Dr. Uffe Ravnskov passed away in 2020. However, his controversial ideas continue to prompt further research and discussions in the field of cardiology and health sciences.

Sales figures for cholesterol lowering drugs are not specifically provided as these numbers often vary based on several factors, such as brand, country, and year. It's important to note that the cholesterol-lowering drugs market, which mainly includes statins, is substantial and has grown over the years.

For example, in 2020, the global cholesterol-lowering drugs market was valued at approximately $36.6 billion, according to Grand View Research. They predict this market will grow at a compound annual growth rate (CAGR) of 7.2% from 2021 to 2028.

Statins, in particular, have consistently had strong sales. Lipitor, produced by Pfizer, yes Pfizer, is one of the top-selling cholesterol drugs and, at its peak, generated over $12 billion in annual sales. Other notable cholesterol drugs with high sales include Crestor by AstraZeneca and Zetia by Merck.

The adverse effects associated with Statins are:
1. Muscle pain and damage: One of the most common complaints of people taking statins is muscle pain. Severe muscle damage, known as rhabdomyolysis, can lead to severe pain and kidney damage.
2. Liver damage: Statins can cause increased levels of liver enzymes, indicating potential damage or inflammation in the liver.
3. Digestive problems: Some people experience nausea, diarrhoea or constipation after starting statin therapy.
4. Increased blood sugar: Statins might increase blood sugar levels, which could lead to type 2 diabetes.
5. Neurological side effects: Some people may experience memory loss or confusion while taking statins.
6. Skin rash or flushing: This is a relatively common side effect.
7. Increased risk of haemorrhagic stroke: While statins can reduce the overall risk of stroke, they seem to increase the risk of a haemorrhagic stroke, which is caused by the rupture of a blood vessel in the brain.
8. Interactions with other medications: Statins can interact negatively with certain other drugs, including some heart medications, leading to serious side effects.

Taking statins is very questionable. I have seen numerous people come off them because of intense fatigue and other adverse effects. They are more likely to deprive the brain of essential cholesterol and may lead to the onset of dementia.
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