TMJ 'dysfunction' - Health implications

Within this forum, you will discover valuable insights on how a 'dysfunctional' jaw, dental arch anomalies, and various body asymmetries can contribute to illness from a unique perspective. This is your go-to resource for finding effective solutions and achieving lasting relief.
It is currently Wed, 02 Apr 2025, 12:50 pm

All times are UTC [ DST ]




Post new topic Reply to topic  [ 1 post ] 
Author Message
PostPosted: Fri, 23 Nov 2012, 10:41 pm 
Offline
Site Admin

Joined: Fri, 28 Sep 2012, 9:08 pm
Posts: 240
Research: brain sizes in twins unaffected by "MS"
Posted: 23 Nov 2012 01:47 AM PST
Kuusisto et al. Volumetric MRI assessment of brain and spinal cord in Finnish twins, discordant for multiple sclerosis. Medicina (Kaunas). 2012;48:437-41.

BACKGROUND: Brain size, white matter hyperintensity, and the development of brain atrophy are known to be highly heritable. The decrease of brain volume starts from the very onset of MS and is 10-fold compared with normal ageing.

AIM: The aim of this study was to assess whether the brain and spinal cord volumes and the volume of white matter lesions differed between twins with MS and their asymptomatic co-twins.

MATERIAL AND METHODS: A co-twin control method was used to evaluate whether the brain and spinal cord volumes differ between twins with MS and their co-twins. Nineteen twin pairs were studied neurologically, and the volumes of T1, T2, FLAIR, and gadolinium-enhanced lesions and those of the brain and the spinal cord were obtained by magnetic resonance imaging.

RESULTS: Significant differences in the brain (P=0.064) or spinal cord (P=0.648) volumes were not detected. Four of the 7 monozygotic/identical and 5 of the 12 dizygotic/non-identical co-twins had focal brain white matter lesions, but none fulfilled the MRI criteria of Barkhof. Spinal cord lesions were not seen in any of the co-twins.

CONCLUSIONS: The absence of a significant difference in the brain or spinal cord volume between the twins with multiple sclerosis and their co-twins supports the recent observation of brain size and the development of brain atrophy being highly heritable.


"A very interesting study, and suggests the unaffected co-twins have sub-clinical brain atrophy despite not having MS. Does this mean they have MS that has not manifested? It would be interesting to see this study reproduced in a larger number of twins."

© 2023 M. Amir All rights reserved


-------------------------------------------------------------------------------------------NOTICE-----------------------------------------------------------------------------------------------
This article is written in accordance with the Human Rights Act 1998: UK Public General Acts 1998 c. 42 SCHEDULE 1 PART I Article 10, with the intent of serving the resilient British public. This legislation clearly states, Everyone has the right to freedom of expression. This right shall include freedom to hold opinions and to receive and impart information and ideas without interference by public authority. We are committed to addressing any form of harassment, whether direct or indirect, by government bodies or their affiliates, in line with this act and the principles that protect freedom of expression. Additionally, any breaches of the Data Protection Act will be promptly reported to the Information Commissioner's Office and The Law Society ..................................................................................................................................................................................................................................
Challenging the existing standards in dental and medical care comes with significant costs. Through my website and this forum, I have highlighted practices that, whether intentionally or unintentionally, contribute to ongoing illness. This disruption is not welcomed by the authorities overseeing our healthcare system. To continue publishing evidence-based articles, sharing discoveries from my own patients' experiences that have led to their recoveries through a unique approach, and educating thousands of health professionals and patients globally, we require some support. If this article has substantially enhanced your understanding, please consider making a donation through this link: PLEASE CLICK TO DONATE

Thank you! A heartfelt thank you to everyone who has generously contributed. Your support is deeply valued and enables Dr. Amir to persist in his mission of fostering improved dental and medical practices globally.

Disclaimer: This educational article focuses on health benefits from individual perspectives and doesn't imply widespread results. Important to seek a doctor's advice before taking action. It's meant to enhance, not substitute for, medical advice and doesn't detail all possible uses or risks. Always prioritize professional medical advice over information read here.


Share on FacebookShare on TwitterShare on TuentiShare on SonicoShare on FriendFeedShare on OrkutShare on DiggShare on MySpaceShare on DeliciousShare on TechnoratiShare on TumblrShare on Google+
Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 1 post ] 

All times are UTC [ DST ]


You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum

Search for:
Jump to:  
Rules of the BoardThe teamDelete all board cookies
Disclaimer: Please read our Disclaimer of warranties and limitation of liability
Also see information on Intellectual Property Rights
Before posting, please read our Board Rules
Powered by phpBB® Forum Software © phpBB Group