The cause of multiple sclerosis (MS) and its pathogenesis are unknown, but 2 main theories have emerged: a viral cause and an autoimmune cause. In the past half century, however, research and therapy have been driven by the autoimmune hypothesis.
We propose that MS is not an autoimmune disease but a genetically determined disorder characterized by metabolically dependent neurodegeneration.
Abhijit Chaudhuri, DM, MD, PhD, FACP, FRCP; Peter O. Behan, DSc, MD, FRCP, FACP
Arch Neurol. 2004;61(10):1610-1612. doi:10.1001/archneur.61.10.1610.
Read the full paper here http://www.direct-ms.org/pdf/ImmunologyMS/MS_Not_Autoimmune.pdf
However, I differ from their hypothesis that MS is a "genetically determined disorder characterized by metabolically dependent neurodegeneration".
Interestingly, the popular modal of treatment with immune system killer drugs has resulted in NO CURE for patients but billions of dollars for big pharma every year with this huge fraud upon patients and society with the complicity of health regulatory agencies in almost every country. The final verdict of fraudulent claims of success are:
There is no cure for MS at this time, and an imminent cure is unlikely, says Tyler Smith, M.D., a neurologist and clinical assistant professor at NYU Langone Health in New York City. 3 Nov 2023